BORIS (CTCFL) Human shRNA Plasmid Kit (Locus ID 140690)

SKU TR305184

CTCFL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 140690
• Synonyms: BORIS; CT27; CTCF-T; dJ579F20.2; HMGB1L1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CTCFL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 140690). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001269040, NM_001269041, NM_001269042, NM_001269043, NM_001269044, NM_001269045, NM_001269046, NM_001269047, NM_001269048, NM_001269049, NM_001269050, NM_001269051, NM_001269052, NM_001269054, NM_001269055, NM_080618, NR_072975, NM_080618.1, NM_080618.2, NM_080618.3, NM_001269055.1, NM_001269051.1, NM_001269052.1, NM_001269050.1, NM_001269047.1, NM_001269054.1, NM_001269049.1, NM_001269048.1, NM_001269046.1, NM_001269045.1, NM_001269042.1, NM_001269040.1, NM_001269041.1, NM_001269044.1, NM_001269043.1, BC060763, BC130486, BC137482, BC137483, NM_001269055.2, NM_001269050.2
• UniProt ID: Q8NI51
• Summary: CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient